PEDIATRICS Vol. 38 No. 5 November 1966, pp. 913-916
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The Association of Indirect Inguinal Hernia with Congenital Cytomegalic Inclusion Disease

DAVID J. LANG M.D.1

1 Massachusetts General Hospital, Boston, Massachusetts 02114

In 1956 and 1957 the isolation of agents responsible for cytomegalic inclusion disease (CID) in man was accomplished almost simultaneously in three laboratories. This group of viruses apparently consists of several related, although serologically distinct, agents. Information has now accumulated with regard to their properties as well as their relationship to clinical disease.

In 1964 Medearis described characteristics of congenital infections induced by cytomegaloviruses in eight children. Seven of the eight cases discussed in that report exhibited symptoms on the first day of life, and, of these congenitally infected infants, all the males manifested inguinal hernias in infancy.