PEDIATRICS Vol. 38 No. 2 August 1966, pp. 201-206
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SUDDEN UNEXPECTED DEATH IN INFANCY AND VIRAL INFECTION

Piero C. Balduzzi M.D.1 and Robert M. Greendyke M.D.1

1 Department of Microbiology and Pathology, University of Rochester School of Medicine and Dentistry, Strong Memorial Unit of the Monroe County Health Department Laboratories, and The Office of the Medical Examiner, County of Monroe, Rochester, New York

The relationship between sudden, unexpected death of infants and enteric viruses was investigated. A total of 97 cases of sudden deaths and 33 "control" cases, comparable from several points of view, were studied.

One viral strain was found in the stool of a "control" case and 14 agents were isolated from the sudden death group; 9 strains were found in stools and 5 strains, all Coxsackie B, were isolated from organ tissues obtained at necropsy. While this last finding suggests that enteric viruses may cause sudden deaths, the frequency of isolation is too low to be significant in a sample of the size investigated here.

Submitted on November 1, 1965
Accepted on April 1, 1966