PEDIATRICS Vol. 38 No. 1 July 1966, pp. 77-81
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CARCINOMA OF THE THYROID IN CHILDREN AND YOUNG ADULTS: IATROGENIC RELATION TO PREVIOUS IRRADIATION

Sumner Hagler M.D.1, Philip Rosenblum M.D.1, and Arthur Rosenblum M.D.1

1 Division of Pediatrics, Michael Reese Hospital and Medical Center and the Department of Pediatrics, The Chicago Medical School

Fifteen cases of carcinoma of the thyroid and four cases of thyroid adenoma in children and young adults are reported. In all, except one, irradiation had been given to the head, neck, or chest of these patients 5 to 17 years previously.

These observations suggest that carcinoma of the thyroid in children is related to irradiation, often prescribed for uncertain therapeutic effect. Irradiation to the head, neck, or chest of infants and children should be avoided wherever possible.

We believe these cases represent a remarkably high incidence of thyroid neoplasia to occur in a single practicing pediatric office. The practicing pediatrician who now follows his patients longitudinally from infancy through adolescence has a unique opportunity to observe the development of disease, even years later.

Submitted on January 10, 1966
Accepted on February 18, 1966




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