1 Director, Clinical Research Center, Children's Hospital Research Foundation, Cincinnati, Ohio
We wish to comment on the last two paragraphs of R. R. Townley's excellent article, "Quantitative Assay of Disaccharidase Activities of Small Intestinal Mucosal Biopsy Specimens in Infancy and Childhood."
Although our experience with the biopsy procedure is somewhat less (176 biopsies) than that of Dr. Townley and his associates in Victoria and Boston, it has been collected entirely with the Crosby-Kugler capsule. We believe we are correct that many, if not the majority, of the 500 biopsies composing the composite series mentioned in Dr. Townley's paper were obtained with the Rubin biopsy tube, since that is the instrument most extensively used in Victoria and in Boston until relatively recently.