PEDIATRICS Vol. 36 No. 6 December 1965, pp. 958
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Pulmonary Vasoconstriction and the Pharmacology of Respiratory Distress

Edward C. Defoe M.D.1

1 Department of Pediatrics, University of Minnesota minneapolis, Minnesota

The stimulating controversy over the R.D.S. problem between Dr. Ivanhoe and Dr. Clements and associates (Pediatrics, 36:451, 1965) prompts expression of a few additional thoughts.

Through a proponent of the theory that the basic problem in these infants is lack of normal sympathetic neurohormonal activity at time of initial inspiratory efforts, I must agree with Dr. Clements that direct evidence for such a deficiency is tenuous. However, the evidnce cited1 against the possibility is questionable.




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