PEDIATRICS Vol. 36 No. 6 December 1965, pp. 821-824
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WATER, AND SALT AND WATER: A DISTINCTION SHOULD BE MADE

Malcolm A. Holliday M.D.1

1 Children's Hospital Medical Center of Northern California, Oakland, and Department of Pediatrics, University of California School of Medicine San Francisco

It is nearly fifty years since Blackfan and Maxcy1 reported the recovery of nine infants with diarrheal dehydration who had been given isotonic saline intraperitoneally. The dramatic impact this had on the recovery rate of this disease is made apparent by noting that in the two previous years there had been reports describing the high mortality in infants with diarrheal dehydration when given alkali to correct the acidosis but nothing to correct the dehydration. Schloss and Stetson noted that mortality remained at 86% despite correction of chemistry. Howland and Marriott commented that "the administration of soda . . . will often overcome both the clinical and laboratory evidence of acidosis.




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 Arch. Dis. Child.Home page
M. A Holliday, P. E Ray, and A. L Friedman
Fluid therapy for children: facts, fashions and questions
Arch. Dis. Child., June 1, 2007; 92(6): 546 - 550.
[Abstract] [Full Text] [PDF]