PEDIATRICS Vol. 36 No. 4 October 1965, pp. 632-634
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Herpangina: The Etiologic Spectrum

James D. Cherry M.D.1 and Charles L. Jahn M.D.2

1 John A. Hartford Foundation Research Laboratory, Madison General Hospital and the Department of Pediatrics, University of Wisconsin School of Medicine, Madison, Wisconsin 1300 University Avenue, Madison, Wisconsin
2 John A. Hartford Foundation Research Laboratory, Madison General Hospital and the Department of Pediatrics, University of Wisconsin School of Medicine, Madison, Wisconsin 1300 University Avenue, Madison, Wisconsin

The etiology of herpangitic enanthem cannot be restricted to certain Coxsackie A viruses. Zahorsky1, 2 and others3-5 considered herpangina a specific febrile disease, but in light of more recent studies6-17 and the presently reported cases, it would seem more appropriate to restrict the use of the term "herpangina" to the description of the characteristic oropharyngeal lesions. Enanthem is one of the protean manifestations of enterovirus infection and is must be included along with other signs and symptoms in the over-all differential diagnosis of summer febrile illness.