PEDIATRICS Vol. 36 No. 3 September 1965, pp. 367-373
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ENVIRONMENTAL TEMPERATURE, OXYGEN CONSUMPTION, AND CATECHOLAMINE EXCRETION IN NEWBORN INFANTS

Leo Stern M.D.1, Martin H. Lees M.D.1, and Jean Leduc M.D.1

1 Joint Cardio-Respiratory Service of the Montreal Children's and Royal Victoria Hospitals, the Department of Paediatrics, McGill University, and the Department of Physiology, University of Montreal

In seven studies of normal newborn infants lowering the evironmental temperature below the neutral range resulted in an increase in metabolism as measured by increased oxygen consumption. Simultaneous with this an increase in urinary noradrenalin excretion was found in all cases.

It is proposed that noradrenalin is the mediator of chemical thermogenesis in the newborn, and that the ability and degree of noradrenalin response at cool environmental temperatures is tile governing factor in the development and maintenance of temperature stability in the newborn infant.

Submitted on November 30, 1964
Accepted on March 4, 1965




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