PEDIATRICS Vol. 36 No. 1 July 1965, pp. 142-144
This Article
Right arrow Full Text (PDF)
Right arrow P3Rs: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when P3Rs are posted
Right arrow Alert me if a correction is posted
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by ESKES, P. W. H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by ESKES, P. W. H.

The Effects of Steroids in the Treatment of Typhoid Fever

PHILIP W. H. ESKES M.D.1

1 Department of Pediatrics, Hôpital Albert Schweitzer, P.O. Box 4, St. Marc, Haiti W.I.

The results are presented of the treatment of 99 infants and children with initially Uncomplicated typhoid fever. The effect of addition of steroids to the chloramphenicol treatment and usual therapeutic regime is discussed. The rapid relief of fever and toxicity, noted eleswhere, was confirmed. This changed our treatment from a mostly inpatient to a mostly outpatient basis, such as is particularly useful, when possible, for hospitals in overcrowded, underdeveloped areas.

The striking reduction in mortality and morbidity in steroid-treated patients warrants further investigation. Caution is recommended in the use of steroids in patients with history of fever for 2 weeks or more, as most typhoid perforations occur in the third week.