PEDIATRICS Vol. 35 No. 6 June 1965, pp. 1022
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Purpura Fulminans

PAOLO TOLENTINO 1

1 Professor of Infectious Diseases, University of Genova, Italy Instituto G. Gaslini Via 5 Maggio, 39, Genoa

I was very interested reading the article "Purpura Fulminans" by Dr. J. D. Bouhasin in Pediatrics, 34:264, 1964. In 1962 I observed a case of purpura fulminans after scarlet fever, which demonstrated a typical hyperfibrinolysis, with dissolution of the coagulum one hour after blood coagulation in vitro, and healed after administration of epsilon-aminocaproic acid. I think this was the first case in the literature in which such a defect could be demonstrated and such therapy was administered. My lesson to the students was published in Minerva Medica, 53:2087, 1962.




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