PEDIATRICS Vol. 35 No. 5 May 1965, pp. 753-758
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SERUM BUTANOL-EXTRACTABLE IODINE CONCENTRATIONS IN PREMATURES

Alan N. Marks M.D.1 and Evelyn B. Man Ph.D.1

1 Department of Pediatrics and Division of Laboratories, Providence Lying-In Hospital, and Institute for Health Sciences, Brown University, Providence, Rhode Island

Normal, full-term neonates have the highest circulating thyroxine-like iodine concentrations observed during the life span of humans (7.2-15.2 µg/100 ml) These elevated serum Butanol-Extractable Iodine concentrations have also occurred in neonates over 2,500 gm in birth weight who required exchange transfusions.

Data are presented on low BEI's of 20 neonates under 2,000 gm in birth weight in a series of 201 BEI measurements on 187 newborns. Mean BEI values increased progressively through 500 gm increments in birth weight from the 2,000-2,500 gm to the 3,500-4,000 gm group, without further rise for infants over 4,000 gm. Requirement of thyroid hormones has been discussed in relation to development of the central nervous system.

Submitted on May 19, 1964
Accepted on December 29, 1964