PEDIATRICS Vol. 35 No. 2 February 1965, pp. 340-342
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Lactulosuria in the Neonate: A Preliminary Report

JOYCE D. GRYBOSKI M.D.1 and JOHN J. BOEHM M.D.2

1 Department of Pediatrics, Yale University School of Medicine New Haven, Connecticut
2 Department of Pediatrics, University of Kentucky Medical Center, Lexington, Kentucky

Urines from 121 neonates were examined for sugars by a high-voltage electrophoresis technique. Lactosuria and maltosuria occurred in 15.4% and 7.7% respectively of infants taking evaporated milk formula. Lactosuria occurred in 21.6% of infants receiving Similac and in 28.6% of the breast-fed infants. Lactulose, a sugar not previously described in urines of normal newborns, was present in the urine of 15.4% of infants taking evaporated milk and in 38.6% of infants taking Similac.