PEDIATRICS Vol. 35 No. 2 February 1965, pp. 284-294
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SPONGY DEGENERATION OF THE NERVOUS SYSTEM (CANAVAN'S DISEASE)

Report of a Case in an Irish-American Family

Gwendolyn R. Hogan M.D.1 and Edward P. Richardson Jr. M.D.1

1 Departments of Neuropathology-Neurology and Pathology, Harvard Medical School, the Charles S. Kubik Laboratory for Neuropathology of the James Homer Wright Pathology Laboratories, and the Joseph P. Kennedy, Jr., Memorial Laboratories, Massachusetts General Hospital, Boston

The clinical and pathological findings in a case of spongy degeneration of the nervous system (Canavan's disease) occurring in an Irish family are presented. The literature is reviewed and the clinical findings that would aid in diagnosis are discussed.

Submitted on July 20, 1964
Accepted on August 15, 1964




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