PEDIATRICS Vol. 35 No. 2 February 1965, pp. 276-283
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CONGENITAL TOXOPLASMOSIS WITH PLACENTAL INFECTION IN MONOZYGOTIC TWINS

Lewis Glasser MC1 and Basil G. Delta MC, FAAP1

1 Laboratory and Pediatric Services, Walson Army Hospital, Fort Dix, New Jersey

An instance of congenital toxoplasmosis affecting identical twin male infants is reported.

This is the first recorded prospective diagnosis of congenital toxoplasmosis discovered by chance histologic observation of the organisms in the placenta. The placental findings enabled an early detection of the disease through close follow-up of the asymptomatic infants. The disease became manifest in both infants simultaneously at the age of 7 months and had a similar course.

Placental toxoplasmosis means fetal infection. Prompt treatment of the infant, even though no symptoms are apparent, may prevent or reduce the degree of permanent oculocerebral damage.

Submitted on June 3, 1964
Accepted on September 19, 1964