1 University College Hospital Medical School, University Street, London, W.C.1.
The report of two cases of homocystinuria by Gerritsen and Waisman (Pediatrics, 33: 413, 1964) raises an important clincal point. The two cases reported by myself and others (Arch. Dis. Child., 38: 425, 1963) both had bilaterally dislocated lenses and this abnormality has been present in all other cases seen by us since then. Gerritsen and Waisman do not make entirely clear statements with respect to eye abnormalities in their patients. For case K.T. we are only told "There was no complaint of any visual difficulty" (p. 415), and nothing is said about the examination of the eye.