PEDIATRICS Vol. 34 No. 3 September 1964, pp. 423-424
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Preliminary Observations on the Prenatal Administration of Demethylchlortetracycline HCI

JOHN C. MACAULAY M.D.1 and JOSEPH A. LEISTYNA M.D.1

1 The Pediatric Clinic, 421 Main Street Oneida, New York

Prenatal administration of tetracycline has previously been reported to cause staining of the infants' teeth. Demethylchlortetracycline has not previously been implicated. Five cases are presented in which demethylchlortetracycline was administered prenatally. In each case, there was staining of those teeth that were undergoing mineralization at the time the drug was administered.