1 The Sharon Cardiovascular Unit and the Endocrine Division of the Children's Hospital Medical Center and the Department of Pediatrics, Harvard Medical School, Boston, Massachusetts
1. Cardiovascular disease associated with Turner's syndrome is more frequent than hitherto reported. In this study, 36 patients were investigated and it was found that in 16 (44%) there was some form of cardiovascular abnormality.
2. Pulmonic stenosis was found to be as frequent as the more commonly reported coarctation of the aorta.
3. Patients with typical Turner's syndrome, who are chromatin negative, may have coarctation of the aorta or pulmonic stenosis. When buccal smears are chromatin positive, stature is within normal limits, or hypertelorism is present, the most likely cardiovascular lesion will be pulmonic stenosis.
Submitted on August 1, 1963
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