PEDIATRICS Vol. 33 No. 2 February 1964, pp. 271-275
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THE EFFECT OF PROMAZINE ON THE ACTIVITY LEVEL OF RETARDED CHILDREN

Jerome L. Schulman M.D.1 and Sister Mary Clarinda O.S.F.2

1 The Child Development Clinic, Children's Memorial Hospital
2 The Department of Pediatrics, Northwestern University Medical School, Chicago

Promazine was administered to six hyperactive retarded boys in a long-term double-blind study. There were four dose levels —40, 60, 80, and 160 mg per day. The effect on activity level was measured with actometers. There was no effect on daytime activity when the placebo and drug levels were compared. There was a significant but clinically unimportant effect on night time activity.

Submitted on June 27, 1963
Accepted on July 25, 1963