This volume contains the proceedings of a Conference sponsored by the National Institutes of Health and the University of Utah and held at Salt Lake City in 1960. It is, in the words of the Editor, "Not quite a complete compendium for experts nor a treatise for beginners . . . ," yet it will provide useful material both for the professional human geneticists and the novice. Sixteen presentations dealing with the methodology of various areas of human genetics are interspersed with discussions from others of the forty-five participants.