PEDIATRICS Vol. 32 No. 4 October 1963, pp. 580-587
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MILK ALLERGY

III. Immunological Studies with Sera from Allergic and Normal Children

S. Saperstein Ph.D.1, D. W. Anderson Jr. Ph.D.1, A. S. Goldman M.D.1, and W. T. Kniker M.D.1

1 Department of Pediatrics, University of Texas Medical Branch, Galveston, Texas

The examination of sera from milk allergic children, children allergic to substances other than milk, and normal children, revealed no significant differences relative to coated tanned cell hemagglutinin titer or the presence of precipitating antibody as measured by gel diffusion for milk components.

The passive cutaneous anaphylaxis test revealed a high percentage of positive responses with sera from milk allergic individuals only.

The presence of milk hemagglutinins could not be demonstrated in the cord sera from 30 newborns.

The results of this study suggest that the passive cutaneous anaphylaxis technique deserves further evaluation as a laboratory method for the confirmation of milk allergy.

Accepted on April 24, 1963