PEDIATRICS Vol. 32 No. 3 September 1963, pp. 371-375
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CHANGES IN RED CELL ENZYME ACTIVITY IN RELATION TO RED CELL SURVIVAL IN INFANCY

Eugene Kaplan M.D.1 and J. Tyson Tildon B.S.2

1 Department of Pediatrics of the Sinai Hospital of Baltimore, Baltimore, Maryland
2 Department of Pediatrics of the Johns Hopkins School of Medicine, Baltimore, Maryland

The change in activity of red cell G6PDH and AChE in normal full term infants forms a pattern which parallels that of Cr51 red cell life span in the first months of life. These two phenomena, one relating to erythrocyte biochemistry and the other to erythrocyte function, are in keeping with the hypothesis that reduced erythropoiesis after birth results in an older red cell population.

Submitted on January 28, 1963
Accepted on April 25, 1963