The chapter headings of this book bespeak its quality: Incidence and Inheritance, by Eugene Knox; Biochemistry, by Marvin Armstrong; chapters on The Clinical Picture, the Pathology and the Pathogenesis of the Mental Defect, by George Jervis; on the Detection, Tests and Reagents, by Willard Centerwall, Helen Berry, and L. I. Woolf; the Management, by Horst Bickel and W. Grüter; a chapter on Diets and Recipes, by Frank Lyman; and, finally, The Experimental Approach, by Harry Waisman. It is clear that the leading authorities on the various aspects of the disease have been tapped and given space to tell their story. An introductory chapter on the discovery of the disease by Siegried and Willard Centerwall gives a charmingly written picture of Asbjörn Fölling"the man who started it all."