1 Departments of Pediatrics and Radiology, State University of New York, Downstate Medical Center, Brooklyn
Twenty Negro infants and young children with sickle-cell disease had crises characterized by painfully swollen hands and/or feetthe "hand-foot" syndrome. Usually within 7 to 14 days periosteal elevation and areas of bone destruction appeared in the metatarsals, metacarpals, and phalanges. The swelling subsided in about 1 to 3 weeks, and the roentgenographic changes in about 3 months. Thirty-two cases reported by other authors are reviewed.
Submitted on July 30, 1962
This article has been cited by other articles:
![]() |
M.C.G. Stevens, M. Padwick, and G.R. Serjeant Observations on the Natural History of Dactylitis in Homozygous Sickle Cell Disease Clinical Pediatrics, May 1, 1981; 20(5): 311 - 317. [Abstract] [PDF] |
||||