PEDIATRICS Vol. 31 No. 5 May 1963, pp. 754-757
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NEUTROPENIA IN AN INFANT SECONDARY TO HYDROCHLOROTHIAZIDE THERAPY: WITH A REVIEW OF HEMATOLOGIC REACTIONS TO "THIAZIDE" DRUGS

Marilyn G. Schotland M.D.1 and Melvin M. Grumbach M.D.1

1 Department of Pediatrics, Columbia University, College of Physicians and Surgeons, and The Babies Hospital, New York City, New York

A 10-month-old infant had an asymptomatic maturation arrest of granulopoiesis secondary to hydrochlorothiazide therapy. In view of the absence of symptoms in this case and the possible lethal consequences, periodic examinations of the blood in patients receiving long-term "thiazide" treatment appears to be warranted.

Submitted on July 24, 1962
Accepted on October 8, 1962




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