PEDIATRICS Vol. 3 No. 5 May 1949, pp. 639-644
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PENICILLIN TREATMENT OF DIPHTHERIA CARRIERS

SAMUEL KARELITZ M.D.1 and VINCENT A. SPINELLI M.D.1

1 The Willard Parker Hospital, New York, N.Y.

Penicillin administered intramuscularly in doses of 30,000 u. every three hours and concurrently in the form of nose drops 1,000 u./ml. in each nostril every two hours effectively eliminated C. diphtheriae from seven carriers and one case of faucial diphtheria within 36 hours. One carrier required five days of therapy.

Penicillin is an effective agent in shortening the period of the carrier state of chronic diphtheria carriers.

Submitted on August 16, 1948