PEDIATRICS Vol. 3 No. 4 April 1949, pp. 573
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The Parathyroid Glands and Metabolic Bone Disease

LAWSON WILKINS

About 25 years ago Fuller Albright became interested in disorders of the parathyroid glands and other conditions disturbing calcium and phosphorus metabolism. It was in 1925 that the first parathyroid adenoma was removed in Vienna and in 1924 and 1925 that Hanson and Collip independently extracted the active principle of the parathyroid glands. Since this time Albright and a long retinue of coworkers have turned out a large number of classic papers clarifying the understanding of the actions of parathyroid hormone, vitamin D and dihydrotachysterol, the effects of various renal disorders upon phosphorus and calcium, and the nature of bone diseases such as osteitis fibrosa generalisata, osteoporosis, osteomalacia, Paget's disease and polyostatic fibrous dysplasia. The new monograph presents in clear and concise form the accumulation of a quarter century of investigations and gives Albright's views as they stand today.