PEDIATRICS Vol. 29 No. 3 March 1962, pp. 500
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Catecholamines, T-Waves, and Newborn Infants

Antonio Marini M.D.1 and Sergio Alessandri M.D.2

1 Department of Pediatrics, University of Pavia, Italy
2 Department of Obstetrics and Gynecology, University of Bologna, Italy

The electrocardiogram of the newborn infant, taken with right precordial leads, shows upright T-wave. During the first few hours the T-wave becomes diphasic and by the twenty-fourth hour of life becomes negative.1-3

Very interesting studies by Lind in newborn humans and pigs and human fetuses have shown that the administration of catecholamines can induce upright T-waves in the right precordial leads at 24 hours. This phenomenon is supposedly related to the effect of the sympatheticomimetic amines (? epinephrine) upon pressure in the pulmonary circulation.4-6