PEDIATRICS Vol. 29 No. 2 February 1962, pp. 332
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In Reply: Indications for and Risks of Replacement Transfusion

Lester Wishingrad M.D.1 and Lawrence D. Elegant M.D.1

1 Chicago, Illinois

We agree with most of the points that are so ably made in the letter of Drs. Newman and Gross. We do not consider "a positive Coombs test sufficient indication for an exchange transfusion in an erythroblastic infant born into a family in which previously affected siblings have required exchange transfusions." We did say, however, that "if a family has a previous history of severe erythroblastosis, the baby is Rh positive, and the result of Coombs test is positive, we find early replacement transfusion essential."