1 Department of Neurology, Wayne State University, College of Medicine, and the Detroit Memorial Hospital, Detroit
The clinical and electroencephalographic signs of leucine-induced hypoglycemia in the infant can be alleviated with oral or intravenous administration of sodium glutamate. The improvement occurs in spite of low glucose levels in plasma after intravenous administration; this supports the view that glutamic acid is rapidly metabolized by the brain during hypoglycemia.