PEDIATRICS Vol. 28 No. 2 August 1961, pp. 293-306
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PATHOLOGIC ANATOMY OF COMPLETE TRANSPOSITION OF THE ARTERIAL TRUNKS

Maurice Lev M.D.1, Victor M. Alcalde M.D.1, and Thomas G. Baffes M.D.1

1 Congenital Heart Disease Research and Training Center, Hektoen Institute, and the Departments of Pathology and Surgery of the Children's Memorial Hospital, and the Departments of Pathology of Northwestern University Medical School and the University of Chicago School of Medicine

A study was made of the pathologic anatomy in 147 cases of complete transposition of the arterial trunks. A classification was attempted, dependent upon the extent and nature of ventricular septation and the presence or absence of abnormalities in the atrioventricular orifices. Complete transposition with mitral stenosis or atresia or with common atrioventricular orifice are characteristically associated with pulmonic stenosis and atresia, while complete transposition with tricuspid stenosis or atresia, or with common ventricle, or single ventricle and small outlet chamber are more commonly associated with increased pulmonary flow. The two complexes, complete transposition with common ventricle and that with single ventricle and small outlet chamber, are very closely related pathologically.