1 Thorndike Memorial Laboratory, Boston City Hospital, Department of Medicine, Harvard Medical School, Boston, Mass.
Splenectomy is now recognized as an essential part of the management of several types of hemolytic anemia, thrombocytopenic purpura, other hemorrhagic diseases and splenomegaly of diverse origin. It is now considered to be the only safe procedure for rupture of the spleen, which is usually, though not always, the result of trauma. In some of the congenital hematologic disorders, the manifestations may be severe enough at or soon after birth to require the operation early in infancy. In these and in the older children the operation usually, but not always, produces prolonged or permanent improvement or remissions that result in more nearly normal growth, development and general well being, reduces or eliminates the requirements for transfusions and, in many of the conditions, prolongs life.
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R. E. Thompson Acquired Hemolytic Anemia: A Review of 26 Cases, including 5 of the Hemolytic-Uremic Syndrome, with Emphasis on the Usefulness of Steroids in Therapy Clinical Pediatrics, May 1, 1967; 6(5): 288 - 294. [PDF] |
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