1 Research Laboratories Parke, Davis & Company, Ann Arbor, Michigan
The primary purpose of this communication is to describe some rather simple procedures for calculating pediatric doses when they are proportional to a fixed power of body weight. It is generally recognized that dose requirements per unit of body weight are usually higher for children than for adults. Consequently the total dose is not directly prportional to the body weight, but appears to be more nearly proportional to the body surface area. This requires preliminary estimation of the body surface area with the assistance of various charts and tables, following which the dose can be calculated by simple proportion when the adult dose is known.
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G. B. Stickler Drug Dosage: A Review of a Problem in Pediatrics Clinical Pediatrics, October 1, 1964; 3(10): 574 - 577. [PDF] |
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