PEDIATRICS Vol. 27 No. 3 March 1961, pp. 378-389
This Article
Right arrow Full Text (PDF)
Right arrow P3Rs: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when P3Rs are posted
Right arrow Alert me if a correction is posted
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Cornblath, M.
Right arrow Articles by Gordon, H. H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Cornblath, M.
Right arrow Articles by Gordon, H. H.

STUDIES OF CARBOHYDRATE METABOLISM IN THE NEWBORN INFANT

III. Some Factors Influencing the Capillary Blood Sugar and the Response to Glucagon during the First Hours of Life

Marvin Cornblath M.D.1, Angelita F. Ganzon M.D.1, Demetrios Nicolopoulos M.D.1, Gloria S. Baens M.D.1, Richard J. Hollander M.D.1, Mordecai H. Gordon Ph.D.1, and Harry H. Gordon M.D.1

1 Departments of Pediatrics of Sinai Hospital of Baltimore, and Johns Hopkins Medical Institutions

Sugars in capillary blood were measured during the first hours of life in full-term infants delivered vaginally and by cesarean section. Pretreatment with dextrose solution for mothers delivered vaginally did not affect the course of the sugar in blood significantly Pretreatment with dextrose or saline solution for mothers delivered by cesarean section produced significant differences in the course of the infants' sugar in blood when compared to each other.

Full-term infants delivered vaginally who were more than 6 hours old had a greater hyperglycemic response to glucagon, 30 µg/kg, than infants less than 3 hours of age.

Full-term infants delivered by elective cesarean section without previous labor responded to 30 µg/kg of glucagon with a diminished hyperglycemia as compared to infants delivered vaginally.

An exposure to labor influenced the neonates' response to glucagon, whereas neither pretreatment of the mother nor the course of sugar in blood were associated with this response.

With large doses of glucagon, 300 µg/kg, the response differences associated with mode of delivery and maturity were not found to be significant.