PEDIATRICS Vol. 26 No. 2 August 1960, pp. 219-224
This Article
Right arrow Full Text (PDF)
Right arrow P3Rs: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when P3Rs are posted
Right arrow Alert me if a correction is posted
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Lüders, D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Lüders, D.

HISTOLOGIC OBSERVATIONS IN ERYTHEMA TOXICUM NEONATORUM

Dieter Lüders M.D.1

1 Department of Pediatrics, Boston University School of Medicine, and the Pediatric Service, Boston City Hospital

The first histologic description of lesions of erythema toxicum neonatorum is given. It is shown that erythema toxicum neonatorum is related to the pilo-sebaceous follicle. The histologic picture is quite different from that of other rashes considered in the discussion of the clinical differential diagnosis.

The papule of erythema toxicum neonatorum shows an accumulation of leukocytes with a predominance of eosinophils within the layers of the hair follicle just below the dermal-epidermal junction of the skin. The pustule of erythema toxicum neonatorum is the result of an accumulation of these cells within the superficial epidermis encircling the hair. The papulo-pustular lesion shows also histologically a combination of both components. The microscopic changes associated with the macule and erythema are meager; only a few perivascular eosinophils are present in the dermis.

The cause of erythema toxicum neonatorum is unknown.