PEDIATRICS Vol. 25 No. 5 May 1960, pp. 807-811
This Article
Right arrow Full Text (PDF)
Right arrow P3Rs: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when P3Rs are posted
Right arrow Alert me if a correction is posted
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Bodansky, O.
Right arrow Articles by Jacobs, A. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Bodansky, O.
Right arrow Articles by Jacobs, A. M.

COMPARISON OF ACTIVITIES OF ISOCITRIC DEHYDROGENASE AND GLUTAMIC-OXALACETIC TRANSAMINASE IN SERUM IN INFECTIOUS HEPATITIS

Oscar Bodansky M.D.1, Morton K. Schwartz Ph.D.1, Saul Krugman M.D.1, Joan P. Giles M.D.1, and A. Milton Jacobs M.D.1

1 Division of Metabolism and Enzyme Studies, Sloan-Kettering Institute for Cancer Research; the Department of Pediatrics, New York University, and the Willowbrook State School, Staten Island, New York

Activities of isocitric dehydrogenase (ICD) and glutamic-oxalacetic transaminase (GOT) in serum were determined concurrently and sequentially in 42 patients exposed to hepatitis virus.

In nine patients who developed clear clinical evidence of the disease, the maximal values for both enzymes were attained on the same day, but the relative rise in GOT was substantially greater. Considerations are presented for the preferential use of the latter enzyme as an aid in diagnosis of hepatitis.

Submitted on June 20, 1959
Accepted on November 8, 1959