PEDIATRICS Vol. 25 No. 4 April 1960, pp. 582-591
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PRIMARY HYPEROXALURIA

I. Clinical and Pathologic Findings in a Patient with Calcium Oxalate Nephrocalcinosis

Thomas H. Shepard II M.D.1, S. Allison Creighton M.D.2, Edwin G. Krebs M.D.3, Lou-sein W. Lee M.S.3, and Horace C. Thuline M.D.2

1 Department of Pediatrics, School of Medicine, University of Washington
2 Department of Pathology, Children's Orthopedic Hospital, Seattle
3 Department of Biochemistry, School of Medicine, University of Washington

The clinical and pathologic findings in a case of primary hyperoxaluria and calcium oxalate nephrocalcinosis in a 7-year-old boy are described and discussed in relation to similar reported cases. The diagnosis was suspected because of nephrocalcinosis in the absence of an abnormality of calcium metabolism and proven by the demonstration of increased urinary excretion of oxalate. Splenomegaly and yellow deposits in the Meibomian glands are described.

Submitted on May 18, 1959
Accepted on September 15, 1959


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A. W. MCLAURIN, W. R. BEISEL, G. J. MCCORMICK, R. SCALETTAR, and R. H. HERMAN
Primary Hyperoxaluria
Ann Intern Med, July 1, 1961; 55(1): 70 - 80.
[Abstract] [PDF]