PEDIATRICS Vol. 25 No. 1 January 1960, pp. 106-111
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C-REACTIVE PROTEIN IN THE SERUM IN NEPHROSIS AND ACUTE GLOMERULONEPHRITIS

Aree Valyasevi M.D.1, Joseph M. Sloan M.D.1, and Lewis A. Barness M.D.1

1 Driscoll Foundation, Children's Hospital, Corpus Christi, Texas, and Department of Pediatrics, University of Pennsylvania Medical School

C-reactive protein in the serum and the erythrocyte sedimentation rate were followed serially in 13 patients with acute nephritis and in 9 patients with the nephrotic syndrome.

Although a positive C-reactive protein test was always associated with evidence of infection, obvious infection in a few instances was not accompanied by a positive test.

Determination of C-reactive protein is valuable in determining the presence of infection in patients with acute nephritis and the nephrotic syndrome, especially in the latter where hormone therapy may mask many signs of infection.

Submitted on April 7, 1959
Accepted on July 1, 1959