PEDIATRICS Vol. 24 No. 2 August 1959, pp. 254-257
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ABSENT SPLEEN SYNDROME

Hematologic Findings as an Aid to Diagnosis

Donald W. Polhemus M.D.1 and William B. Schafer M.D.1

1 Department of Pediatrics, Childrens Hospital, Los Angeles, and the University of Southern California School of Medicine

The syndrome of congenital absence of the spleen with atrioventricularis communis and partial transposition of the abdominal viscera is briefly discussed. Because of absence of the spleen, these patients have been found to exhibit specific abnormalities of peripheral blood, namely, normoblastemia and Howell-Jolly bodies and Heinz bodies in the erythrocytes. A case is presented illustrating the method of making a diagnosis based upon the hematologic findings.

Submitted on January 19, 1959
Accepted on February 17, 1959