PEDIATRICS Vol. 23 No. 4 April 1959, pp. 755
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Leukämie im Kindesalter. Bettrage zur Morphologie, Klinik Pathophysiologie und Therapie

CARL H. SMITH M.D.

Based on an experience of 191 cases of leukemia in the past 13 years, the authors have prepared a well-organized book dealing with the essential features of leukemia in childhood. As would be expected the bulk of cases are the acute leukemias which they term acute leukocytic, undifferentiated or paraleukoblastosis; a small number are acute promyelocytic, chronic myelocytic and rare types. In common with the experience from other clinics the incidence of leukemia rose from 0.159% in 1946 to 0.546% in 1956.

The authors have written a readable and timely text dealing concisely with the following subjects: pathologic anatomy and hematology, clinical aspects, individual organ changes, leukemia and infection, differential diagnosis, the newer knowledge relating to etiology and therapy, metabolic aspects, prognosis and psychologic aspects in management. In each chapter current information has been assembled, this being especially noticeable in discussion of etiology and therapy.