In this initial volume of a new series of "Advances," the editors state in the preface that their aim "is to provide a readable account of selected important developments [in clinical chemistry], of their roots in the allied fundamental disciplines, and of their impact upon the progress of medical science." The editors have drawn on eminent authorities from Australia, Sweden and Switzerland as well as Great Britain and the United States to contribute nine chapters on a wide variety of subjects. The reviews, which in general are of exceptional quality, provide a critical evaluation of important advances in methods of analysis and their clinical significance. In addition to much useful information on analytic techniques of value to the investigator, the reviews contain a wealth of information clearly and succinctly presented which reflect the authors' thorough syntheses of recent advances in their special fields. The extensive bibliographies include a large number of references in the foreign literature.