PEDIATRICS Vol. 23 No. 3 March 1959, pp. 561-569
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CURRENT MANAGEMENT OF NEPHROSIS

Statistical Evaluation and a Proposed Approach to Therapy

Conrad M. Riley M.D.1 and Peter R. Scaglione M.D.1

1 Department of Pediatrics, College of Physicians and Surgeons, Columbia University, and Babies Hospital, New York

A statistical evaluation is presented, which reveals a significantly improved survival of children with nephrosis under modern management.

The status of the survivors in a small sample seems much better in the current series.

The evidence that such improvement is due to the more intensive use of adrenalactive steroid therapy is circumstantial but highly credible.

A program for steroid administration, which has seemed satisfactory, is presented. The risks inherent in such hormone treatment appear to be more than counterbalanced by the reduction in early mortality.

Submitted on July 28, 1958
Accepted on October 9, 1958