PEDIATRICS Vol. 23 No. 3 March 1959, pp. 507-519
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LUNG VOLUMES OF NORMAL AND ASTHMATIC CHILDREN

John F. Andrewes M.B., D.C.H.1 and Daniel H. Simmons M.D., Ph.D.1

1 Department of Pediatrics, Medicine, and Physiology, University of California Medical Center, and the Veterans Administration Center, Los Angeles

Measurements of the various lung volumes were carried out with 27 normal children, 21 asthmatic children and 4 with allergic rhinitis. The asthmatic children had increases in functional residual capacity and residual volume.

There was a significant increase in the time required for intrapulmonary mixing of gas in the asthmatic subjects.

A biphasic character to the "wash-out" curves in both normal and asthmatic subjects was shown.

It was considered, though not proved, that the increases in lung volume were due to the presence of bronchial obstruction.

Submitted on June 17, 1958
Accepted on September 23, 1958