PEDIATRICS Vol. 23 No. 1 January 1959, pp. 12-17
This Article
Right arrow Full Text (PDF)
Right arrow P3Rs: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when P3Rs are posted
Right arrow Alert me if a correction is posted
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Segar, W. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Segar, W. E.

IDIOPATHIC PAROXYSMAL MYOGLOBINURIA

William E. Segar M.D.1

1 Department of Pediatrics, Indiana University School of Medicine

A case of idiopathic paroxysmal myoglobinuria is reported. This is a disease of unknown etiology, characterized by severe muscle pain and weakness or complete paralysis and by the excretion of burgundycolored urine. The urine is free of erythrocytes but gives a strongly positive benzidine reaction. There is no discoloration of the plasma. A definite diagnosis can be made by spectroscopic examination of the urinary pigment and identification of the absorption bands characteristic of myoglobin.

The underlying pathologic process and clinical manifestations are discussed.

This report describes the treatment of a 15-year-old boy who recovered despite the development of both respiratory paralysis and acute renal failure, complications which are responsible for the mortality rate of 30% from this disorder.

Submitted on May 29, 1958
Accepted on July 2, 1958