PEDIATRICS Vol. 22 No. 6 December 1958, pp. 1170-1182
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THALLIUM POISONING

Philip H. Chamberlain M.D.1, William B. Stavinoha B.S., M.S.1, Helen Davis M.D.1, William T. Kniker M.D.1, and Theodore C. Panos M.D.1

1 Departments of Pediatrics and Pharmacology and Toxicology, University of Texas School of Medicine, Galveston

Fourteen children with thallium poisoning are described.

Alopecia and neurologic symptoms dominate the clinical picture. In the absence of alopecia, the diagnosis depends upon a high degree of suspicion in regard to any child presenting bizarre neurologic complaints with acute onset.

The best means of confirming a diagnosis of thallotoxicosis is by finding thallium in the urine.

Dithizon appeared to be beneficial treatment in five of six severely ill patients. Further cautious trials of this drug are indicated.

On the basis of the few patients studied, it appears that increased urinary excretion of thallium is not correlated with urine volume, clinical improvement or the use of dithizon.

Submitted on April 9, 1958
Accepted on July 1, 1958




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J. M. Arena, G. A. Watson, and S.S. Sakhadeo
Fatal Thallium Poisoning: A Plea for a Safer Pesticide
Clinical Pediatrics, May 1, 1965; 4(5): 267 - 270.
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