PEDIATRICS Vol. 22 No. 4 October 1958, pp. 727-737
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CONGENITAL SUBGLOTTIC HEMANGIOMAS OF THE LARYNX AND TRACHEA IN INFANTS

J. S. Campbell M.D.1, F. W. Wiglesworth M.D.2, Rocco Latarroca M.D.3, and Henry Wilde M.D.4

1 Department of Pathology, University of Ottawa., (J.S.C.) General Hospital, Bruyère Street, Ottawa 2, Ontario, Canada.
2 Departments of Pathology of Montreal Children's Hospital and McGill University., (J.S.C.) General Hospital, Bruyère Street, Ottawa 2, Ontario, Canada.
3 Departments of Pathology of Mount Auburn Hospital, Cambridge, Massachusetts, and Tufts University Medical School, Boston., (J.S.C.) General Hospital, Bruyère Street, Ottawa 2, Ontario, Canada.
4 (J.S.C.) General Hospital, Bruyère Street, Ottawa 2, Ontario, Canada.

Our experience with five cases of congenital subglottic hemangioma is amplified by a review of 14 previously reported cases. The 19 patients were all less than 1 year of age, and 12 of them were girls. All showed evidence of laryngeal obstruction, which was usually episodic and usually sufficiently severe to require tracheotomy. Detection of subglottic stenosis by roentgenographic, laryngoscopic or bronchoscopic examinations permitted clinical diagnosis to be made in 11 cases, in 7 of which recovery or clinical improvement was attained by roentgen or radium therapy, or by surgical excision of the lesion. Twelve patients died: death resulted from asphyxia in eight cases that were undiagnosed or misdiagnosed clinically. Since subglottic hemangiomas have been overlooked at gross post-mortem examination of the larynx, histologic examination of the subglottic region is advocated as a routine necropsy procedure in cases of unexplained death in infancy.

Submitted on February 20, 1958
Accepted on May 3, 1958




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A. Kahn, D. Baran, M. Spehl, I. Dab, and D. Blum
Congenital Stridor in Infancy: Clinical Lessons Derived from a Survey of 31 Instances
Clinical Pediatrics, January 1, 1977; 16(1): 19 - 26.
[Abstract] [PDF]