PEDIATRICS Vol. 21 No. 3 March 1958, pp. 443-444
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HEMOLYTIC DISEASE OF THE NEWBORN DUE TO THE RARE BLOOD FACTOR, rhw(Cw)

M. O. Sacks M.D.1, C. Schlutz 1, L. Dagovitz M.D.1, and M. Vanecko M.D.1

1 Department of Pediatrics of the Little Company of Mary Hospital, Evergreen Park, Illinois, and the Blood Grouping Laboratory of the Michael Reese Research Foundation, Chicago

This case serves to emphasize several features in the management of hemolytic disease of the newborn, including the importance of noting clinical icterus, the importance of proceeding with therapy even though the specificity of the sensitizing antigen is unknown, and the importance of a detailed investigation for the offending antibody. This includes the use of a panel of erythrocytes by personnel practiced in its function. As most blood banks do not have such panels or personnel, it is recommended that studies on cases of hemolytic disease of the newborn, where a serologic diagnosis has not been made, be done in a qualified laboratory. Blood samples should be forwarded to such a laboratory for testing.

Submitted on August 19, 1957
Accepted on September 12, 1957