I noted with interest the report on "Methemoglobinemia Due to Benzocaine" (Pediatrics, 20:915, 1957), apparently caused by an ointment containing benzocaine. I had expected that sooner or later such a case would be reported.
Dr. Wolff referred to a case I reported previously: "Methemoglobinemia in an Infant Associated with Application of a Tar-Benzocaine Ointment" (J. Pediat., 47:22, 1955).
At the time this was reported I was uncertain as to whether the 2
% tar or the 5% benzocaine in the ointment was the toxic factor, and could find no case of methemoglobinemia caused by either substance in ointment or otherwise.
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