PEDIATRICS Vol. 21 No. 1 January 1958, pp. 8-12
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THE PRESENCE OF SERRATIA MARCESCENS AS THE PREDOMINATING ORGANISM IN THE INTESTINAL TRACT OF THE NEWBORN

The Occurrence of the "Red Diaper Syndrome"

Harry A. Waisman Ph.D., M.D.1 and William H. Stone Ph.D.2

1 Department of Pediatrics, School of Medicine (H.A.W.)
2 Department of Genetics, College of Agriculture, University of Wisconsin

An unusual case of gastrointestinal invasion with Serratia marcescens in a newborn is reported. It is suggested that the invasion occurred prenatally or immediately postnatally from airborne contamination by the organism, originating from a neighboring laboratory using the organism in aerosol studies.

The presence of the organism was first recognized by the red pigmentation of of soiled diapers after they had been incubated from 24 to 36 hours in the diaper receptacle.

Shortly after administration of sulfasuxidine and the prescription of a revised diet, the bacteria which produced red pigment were overgrown by the usual bacterial species constituting the "normal" flora of the intestinal tract. At ages greater than 9 months no Serratia marcescens were detectable in the stools of the patient.

The infant developed normally and displayed no adverse effects as a result of the invasion of the intestinal tract by Serratia marcescens.

Submitted on May 13, 1957
Accepted on August 5, 1957




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