PEDIATRICS Vol. 19 No. 3 March 1957, pp. 351-361
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ECZEMA ASSOCIATED WITH THROMBOCYTOPENIC PURPURA AND PURULENT OTITIS MEDIA

Report of Five Fatal Cases

Carolyn C. Huntley M.D.1 and Susan C. Dees M.D.2

1 Dr. Huntley was a Fellow in Pediatric Allergy, Duke University Hospital.
2 Department of Pediatrics, Duke University School of Medicine

The case histories of five male children, who had eczema, thrombocytopenic purpura, and purulent otitis media terminating with death, are reported. Four of the group lived about 2 years, one survived for 7frac12 years. The role of allergy, infection, drug therapy including steroid hormones, and splenectomy is discussed. In three of the group a family history of this symptom complex is compatible with a sex-linked recessive character as was true in Aldrich's case. The hereditary pattern and the combination of symptoms differentiate these patients from the majority of children with either eczema or purpura.

Submitted on May 25, 1956
Accepted on September 12, 1956


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