PEDIATRICS Vol. 19 No. 2 February 1957, pp. 272-284
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SERIOUS UNTOWARD REACTIONS TO THERAPY WITH CORTISONE AND ADRENOCORTICOTROPIN IN PEDIATRIC PRACTICE (PART II)

Robert A. Good Ph.D., M.D.1, Robert L. Vernier M.D.1, and Richard T. Smith M.D.1

1 Department of Pediatrics, University of Minnesota Medical School and Research Laboratories of the Variety Club Heart Hospital

The problem confronting the pediatrician who considers the use of ACTH and cortisone in treatment of a patient is considered.

Serious untoward side reactions observed in the treatment of 340 children with ACTH and adrenocortical hormones are documented.

Potential hazards of treatment with ACTH and adrenocortical hormones, not yet expressed clinically, are indicated.

The implications of these observations in the use of ACTH and steroid hormones in clinical pediatrics are considered.




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